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doi:10.1002/14651858.CD001838.pub6

Here are some of the main roles vitamin B12 plays in health maintenance: In addition to those numerous functions, vitamin B12 also offers critical immune system support

Unfortunately, some patients have difficulty absorbing an adequate amount of vitamin 12 because they do not produce enough stomach acid due to a condition called autoimmune atrophic gastritis which can cause a deficiency of vitamin B12

Cisapride has been effectively withdrawn from use in the US, and the long-term use of metoclopramide is associated with a risk of irreversible tardive dyskinesia, limiting its use in clinical practice